WebPrincipal investigator. Frederick Alt, PhD. Director Program in Cellular and Molecular Medicine at Boston Children's Hospital. Principal Investigator Howard Hughes Medical … WebThe Ferguson lab will work to identify and characterize biomarkers of successful and dysfunctional cognitive function by monitoring and manipulating relevant circuits using Calcium imaging, optogenetics, pharmacogenetics, various slice and in vivo electrophysiology approaches, and behavior. J. X. Z. FILTER BY NEURO TOPICS. …
Faculty Harvard BBS PhD Program
WebFrederick W. Alt Charles A. Janeway Professor of Pediatrics The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more Lab Website Publications Boston Children's Hospital Karp Family Research Building, Rm. 09216 One Blackfan Circle WebFrederick W. Alt Charles A. Janeway Professor of Pediatrics The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune … the contractor movie near me
eccDNAs are apoptotic products with high innate ... - PubMed
WebIn initial experiments we found that a non-hepatotoxic dose of cadmium chloride (CdCl2; 2.0 mg/kg, i.v.) markedly increased the clearance rate of colloidal carbon from the blood, which is indicative of enhanced phagocytic activity by Kupffer cells (resident hepatic macrophages). Thus, the objective these studies was to determine the involvement ... WebThe Alt laboratory studies mechanisms that maintain genomic stability in mammalian cells. The programmed recombination and hypermutation events in lymphocytes and the … WebThe RAG endonuclease initiates Igh V(D)J assembly in B cell progenitors by joining D segments to J H segments, before joining upstream V H segments to DJ H intermediates 1.In mouse progenitor B cells, the CTCF-binding element (CBE)-anchored chromatin loop domain 2 at the 3' end of Igh contains an internal subdomain that spans the 5' CBE … the contractor mars